Miltuximab® for Therapeutic & Imaging Applications
We are examining multiple mechanisms of action including:
- Radio immunotherapy
- Bispecific antibodies
- Immune cell engagement and activation
We have now completed a first in-human trial using Miltuximab®, our anti-GPC-1 monoclonal antibody (ANZCTR registry).
The trial dosed 12 patients and no drug-related adverse events were observed.
Glytuzumab® refers to the humanized version of Miltuximab® and also targets human GPC-1. The Glytuzumab® program is currently undergoing Lead Optimisation and Lead Selection stages. Several humanized leads have been generated with similar binding affinities as that of the parent molecule Miltuximab®. The final Glytuzumab® lead selected will be taken forward from cell line development through to large scale GMP production for future clinical trials.
2015 Eureka Prize
Excellence in Interdisciplinary Scientific Research
Major Australian prize for innovation awarded to our CEO, Brad Walsh, and university collaborators.
We are based in Sydney, adjacent to one of Australia’s leading universities, Macquarie University, and the Macquarie University Hospital, one of our key collaborators.